产品货号:
Z29935
中文名称:
CARD10抗体
英文名称:
Anti-CARD10 Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-CARD10 Antibody |
指标别名 | BIMP1;CARMA3;Caspase recruitment domain-containing protein 10;CARD-containing MAGUK protein 3;Carma 3 |
克隆性 | Polyclonal |
检验物种 | human,mouse |
应用范围 | WB |
基因名称 | CARD10 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Synthesized peptide derived from the Internal region of human CARD 10.at AA rangle:450-530 |
计算分子量 | 116KD |
成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
纯化方式 | Immunogen affinity purified |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | Apoptosis is related to many diseases and development.Cell death signals are transduced by death domain (DD),death effector domain (DED),and caspase recruitment domain (CARD) containing molecules.CARD containing proteins include some caspases,Apaf-1,CARD4,IAPs,RICK,ARC,RAIDD,Bcl-10,and ASC.A novel CARD-containing protein was recently identified and designated CARD10.This protein belongs to the membrane-associated guanylate kinase-like (MAGUK) family of proteins that can function as molecular scaffolds that assist assembly of signal transduction molecules.CARD 10 interacts with Bcl-10,a Bcl protein that promotes apoptosis,caspase-9 maturation and activation of NF-百B.CARD 10 and the related protein CARMA1 also associate with NEMO,the regulatory subunit of the I百K complex,demonstrating its importance in the regulation of NF-百B transcription factor activation. |
Uniprot ID | Q9BWT7 |
基因名全称 | Caspase recruitment domain-containing protein 10 |
推荐稀释比 | WB,1:500~1:2000 |
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